Grindey, Gerald B : rechercher sur Z-Library

Le plus grand référentiel d'articles scientifiques au monde. 70,000,000+ d'articles gratuitement.

Don't use scam websites

Livres
Articles (29)
Les plus populaires
Liste
- Liste
- Tableau

1

Pharmacokinetics of the anticancer agent sulofenur in mice, rats, monkeys, and dogs

William J. Ehlhardt, Hugh R. Sullivan, Paul G. Wood, Joseph M. Woodland, Marta Hamilton, Cristi Hamilton, David Cornpropst, Gerald B. Grindey, John F. Worzalla, Jesse R. Bewley, Glen C. Todd, J. Jeffr

Journal:

Journal of Pharmaceutical Sciences

Année:

1993

Langue:

english

Fichier:

PDF, 740 KB

english, 1993

2

Synthesis and biological evaluation of a new series of dihydrofolate reductase inhibitors based on the 4-(2,6-diamino-5-pyrimidinyl)alkyl-L-glutamic acid structure

Lynn S. Gossett, Lillian L. Habeck, Susan B. Gates, Sherri L. Andis, John F. Worzalla, Richard M. Schultz, Laurane G. Mendelsonn, William Kohler, Manohar Ratnam, Gerald B. Grindey, Chuan Shih

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1996

Langue:

english

Fichier:

PDF, 170 KB

english, 1996

3

Antineoplastic bicyclicsulfonylureas

Fariborz Mohamadi, Michael M. Spees, Gerald B. Grindey

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1992

Langue:

english

Fichier:

PDF, 371 KB

english, 1992

4

Automated measurement of transplantable solid tumors using digital electronic calipers interfaced to a microcomputer

John F. Worzalla, Jesse R. Bewley, Gerald B. Grindey

Journal:

Investigational New Drugs

Année:

1990

Langue:

english

Fichier:

PDF, 814 KB

english, 1990

5

Evaluation of N-(5-indanylsulfonyl)-N′-(4-chlorophenyl)-urea against xenografts of pediatric rhabdomyosarcoma

Peter J. Houghton, Janet A. Houghton, Leann Myers, Pamela Cheshire, J. Jeffry Howbert, Gerald B. Grindey

Journal:

Cancer Chemotherapy and Pharmacology

Année:

1989

Langue:

english

Fichier:

PDF, 498 KB

english, 1989

6

Phase II evaluation of the sulfonylurea LY186,641 in men with hormone independent metastatic prostate cancer

George Wilding, Gerald Grindey, Nikhil Munshi, David Seitz, Lawrence Einhorn

Journal:

Investigational New Drugs

Année:

1993

Langue:

english

Fichier:

PDF, 195 KB

english, 1993

7

Lack of in vivo crossresistance with gemcitabine against drug-resistant murine P388 leukemias

W. R. Waud, Karen S. Gilbert, Gerald B. Grindey, John F. Worzalla

Journal:

Cancer Chemotherapy and Pharmacology

Année:

1996

Langue:

english

Fichier:

PDF, 135 KB

english, 1996

8

Micro procedure for determination of pyrophosphate and orthophosphate

Gerald B. Grindey, Charles A. Nichol

Journal:

Analytical Biochemistry

Année:

1970

Langue:

english

Fichier:

PDF, 306 KB

english, 1970

9

Tritylated oncolytics as prodrugs

Vinod F. Patel, Julie N. Hardin, Gerald B. Grindey, Richard M. Schultz

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1995

Langue:

english

Fichier:

PDF, 296 KB

english, 1995

10

Sulfonimidamide Analogs of Oncolytic Sulfonylureas†,1

Toth, John E., Grindey, Gerald B., Ehlhardt, William J., Ray, James E., Boder, George B., Bewley, Jesse R., Klingerman, Kim K., Gates, Susan B., Rinzel, Sharon M., Schultz, Richard M.

Journal:

Journal of Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 248 KB

english, 1997

11

A dideazatetrahydrofolate analog lacking a chiral center at C-6: N-[4-[2-(2-amino-3,4-dihydro-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5yl)ethyl[benzoyl]-L-glutamic acid is an inhibitor of thymidylate synthase

Taylor, Edward C., Kuhnt, Dietmar, Shih, Chuan, Rinzel, Sharon M., Grindey, Gerald B., Barredo, Julio, Jannatipour, Mehrdad, Moran, Richard G.

Journal:

Journal of Medicinal Chemistry

Année:

1992

Langue:

english

Fichier:

PDF, 620 KB

english, 1992

12

Studies on the cellular pharmacology of N-(4-methylphenylsulfonyl)-N′-(4-chlorophenyl)-urea

Peter J. Houghton, Frank C. Bailey, Glen S. Germain, Gerald B. Grindey, J.Jeffry Howbert, Janet A. Houghton

Journal:

Biochemical Pharmacology

Année:

1990

Langue:

english

Fichier:

PDF, 828 KB

english, 1990

13

Effect of O6-benzylguanine on the sensitivity of human colon tumor xenografts to 1,3-BIS(2-chloroethyl)-1-nitrosourea(BCNU)

M.Eileen Dolan, Anthony E. Pegg, Robert C. Moschel, Gerald B. Grindey

Journal:

Biochemical Pharmacology

Année:

1993

Langue:

english

Fichier:

PDF, 702 KB

english, 1993

14

Characterization of the intracellular distribution and binding in human adenocarcinoma cells of N-(4-azidophenyl-sulfonyl)-N′-(4-chlorophenyl)urea (LY219703), a photoaffinity analogue of the antitumor diarylsulfonylurea sulofenur

Peter J. Houghton, Janek Sosinski, Jay H. Thakar, George B. Boder, Gerald B. Grindey

Journal:

Biochemical Pharmacology

Année:

1995

Langue:

english

Fichier:

PDF, 964 KB

english, 1995

15

Dietary folate and folylpolyglutamate synthetase activity in normal and neoplastic murine tissues and human tumor xenografts

Susan B. Gates, John F. Worzalla, Chuan Shih, Gerald B. Grindey, Laurane G. Mendelsohn

Journal:

Biochemical Pharmacology

Année:

1996

Langue:

english

Fichier:

PDF, 394 KB

english, 1996

16

Whole-body autoradiographic disposition and plasma pharmacokinetics of 5,10-dideazatetrahydrofolic acid in mice fed folic acid-deficient or regular diets

Raymond C. Pohland, Teresa Alati, Ronald J. Lantz, Gerald B. Grindey

Journal:

Journal of Pharmaceutical Sciences

Année:

1994

Langue:

english

Fichier:

PDF, 502 KB

english, 1994

17

Mammalian deoxyuridine 5′-triphosphate pyrophosphatase

Gerald B. Grindey, Charles A. Nichol

Journal:

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis

Année:

1971

Langue:

english

Fichier:

PDF, 220 KB

english, 1971

18

Sulfonylureas: a new class of cancer chemotherapeutic agents

Mohamadi, Fariborz, Spees, Michael M., Grindey, Gerald B.

Journal:

Journal of Medicinal Chemistry

Année:

1992

Langue:

english

Fichier:

PDF, 720 KB

english, 1992

19

Synthesis and biological activity of acyclic analogs of 5,10-dideaza-5,6,7,8-tetrahydrofolic acid

Shih, Chuan, Gossett, Lynn S., Worzalla, John F., Rinzel, Sharon M., Grindey, Gerald B., Harrington, Philip M., Taylor, Edward C.

Journal:

Journal of Medicinal Chemistry

Année:

1992

Langue:

english

Fichier:

PDF, 1.17 MB

english, 1992

20

Clinical pharmacology of the 6-thiopurines

Grindey, Gerald B.

Journal:

Cancer Treatment Reviews

Année:

1979

Langue:

english

Fichier:

PDF, 761 KB

english, 1979

21

Antitumor activity of (2-alkoxyalkyl)- and (2-alkoxyalkenyl)phosphocolines

Bonjouklian, Rosanne, Phillips, Michael L., Kuhler, Kathy M., Grindey, Gerlad B., Poore, Gerald A., Schultz, Richard M., Altom, Marilyn G.

Journal:

Journal of Medicinal Chemistry

Année:

1986

Langue:

english

Fichier:

PDF, 877 KB

english, 1986

22

Comparison of metabolism and toxicity to the structure of the anticancer agent sulofenur and related sulfonylureas

Ehlhardt, William J., Woodland, Joseph M., Worzalla, John F., Bewley, Jesse R., Grindey, Gerald B., Todd, Glen C., Toth, John E., Howbert, J. Jeffry

Journal:

Chemical Research in Toxicology

Année:

1992

Langue:

english

Fichier:

PDF, 977 KB

english, 1992

23

Synthesis and antitumor activity of 5-deaza-5,6,7,8-tetrahydrofolic acid and its N10-substituted analogs

Taylor, Edward C., Hamby, James M., Shih, Chuan, Grindey, Gerald B., Rinzel, Sharon M., Beardsley, G. Peter, Moran, Richard G.

Journal:

Journal of Medicinal Chemistry

Année:

1989

Langue:

english

Fichier:

PDF, 855 KB

english, 1989

24

Anticancer Drugs and Signalling Targets: Principles and Examples

Powis, Garth, Abraham, Robert T., Ashendel, Curtis L., Zalkow, Leon H., Grindey, Gerald B., Vlahos, Chris J., Merriman, Ronald, Bonjouklian, Rosanne

Journal:

Pharmaceutical Biology

Année:

1995

Langue:

english

Fichier:

PDF, 866 KB

english, 1995

25

Cytotoxicity and Antitumor Activity of 2′,2′-Difluorodeoxycytidine (Gemcitabine)

Grindey, Gerald B., Hertel, L. W., Plunkett, W.

Journal:

Cancer Investigation

Année:

1990

Langue:

english

Fichier:

PDF, 89 KB

english, 1990

26

2',2'-Difluorodeoxycytidine Metabolism and Mechanism of Action In Human Leukemia Cells

Plunkett, William, Gandi, Varsha, Chubb, Sherri, Nowak, Billie, Heinemann, Volker, Mineishi, Shin, Sen, Alina, Herte, Larry, Grindey, Gerald

Journal:

Nucleosides Nucleotides & Nucleic Acids

Année:

1989

Langue:

english

Fichier:

PDF, 370 KB

english, 1989

27

Efficacy of sulofenur and a second generation diarylsulfonylurea, N-[5-(2,3-dihydrobenzofuryl) sulfonyl]-N'-(3,4-dichlorophenyl)urea (LY295501), against colon adenocarcinoma xenografts

Houghton, Peter J, Cheshire, Pamela J, Myers, Leann, Lutz, Lois, Toth, John, Grindey, Gerald B, Houghton, Janet A

Journal:

Anti-Cancer Drugs

Année:

1995

Fichier:

PDF, 462 KB

1995

28

Activity of 2, 2 -difluorodeoxycytidine (Gemcitabine) against human tumor colony forming units

Hanauske, Axel-R, Degen, Donna, Marshall, Martha H, Hilsenbeck, Susan G, Grindey, Gerald B, Von Hoff, Daniel D

Journal:

Anti-Cancer Drugs

Année:

1992

Fichier:

PDF, 273 KB

1992

29

Phase I trial of sulofenur (LY186641) given orally on a daily × 21 schedule

Brown, Thomas D, OʼRourke, Timothy J, Kuhn, John G, Craig, Johnny B, Havlin, Kathleen, Burris, Howard A, Cagnola, John, Hamilton, J Michael, Grindey, Gerald B, Satterlee, Winston G, Von Hoff, Daniel D

Journal:

Anti-Cancer Drugs

Année:

1994

Fichier:

PDF, 594 KB

1994